Pesticide-induced immunotoxicity: are Great Lakes residents at risk?

Immunotoxicity of PCBs (Aroclors) in relation to Great Lakes.

Polychlorinated biphenyls (PCBs) are among the most widespread environmental pollutants and a prominent contaminant of the Great Lakes basin. Due to their resistance to biodegradation and lipophilic properties, PCBs bioaccumulate in fish tissues and in fish-eating humans. PCBs are also known to cross the placenta and to be excreted into the mother's milk, thus predisposing the infant to potenti...

Immunotoxicity of heavy metals in relation to Great Lakes.

Heavy metals including mercury, lead, and cadmium are present throughout the ecosystem and are detectable in small amounts in the Great Lakes water and fish. The main route of exposure of humans to these metals is via the ingestion of contaminated food, especially fish. Extensive experimental investigations indicated that heavy metals alter a number of parameters of the host's immune system and...

Fish Consumption and Advisory Awareness in the Great Lakes Basin

More than 61 million adults live in the eight U.S. states bordering the Great Lakes. Between June 2001 and June 2002, a population-based, random-digit-dial telephone survey of adults residing in Great Lakes (GL) states was conducted to assess consumption of commercial and sport-caught fish and awareness of state-issued consumption advisories for GL fish. On the basis of the weighted survey data...

An Assessment of Mirex Concentrations along the Southern Shorelines of the Great Lakes, USA

Mirex is a persistent and toxic polychlorinated pesticide that has compromised environmental quality in the Great Lakes region since the 1960s. As a bioaccumulative and carcinogenic compound, mirex at its current levels in Lake Ontario is a concern because of the potential for trophic level transfer and biomagnification in top predators. As a part of the NOAA’s National Status and Trends Progra...

[Studies on the analysis of pesticide residues in foods (XL). PCB (polychlorinated biphenyls) residues in imported smelt fished from the Canadian Great Lakes].